Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | C32 | 0.0316 | uM | 24 | hr | 2424 | 267 | 1.2471 | 1.0901 | 0.1102 | 0.1588 | 3 |
| SB590885 | C32 | 0.0316 | uM | 24 | hr | 2215 | 342 | 1.0829 | 1.0901 | 0.1544 | 0.1588 | 4 |
| SB590885 | C32 | 0.0100 | uM | 24 | hr | 2059 | 319 | 1.0060 | 1.0475 | 0.1549 | 0.1377 | 2 |
| SB590885 | C32 | 0.0100 | uM | 24 | hr | 2246 | 266 | 1.1448 | 1.0475 | 0.1184 | 0.1377 | 3 |
| PLX-4720 | C32 | 0.3160 | uM | 24 | hr | 1973 | 326 | 0.9522 | 0.9421 | 0.1652 | 0.1737 | 1 |
| SB590885 | C32 | 0.0100 | uM | 24 | hr | 2109 | 263 | 1.0673 | 1.0475 | 0.1247 | 0.1377 | 4 |
| SB590885 | C32 | 0.3160 | uM | 24 | hr | 2219 | 460 | 1.0170 | 0.9712 | 0.2073 | 0.2246 | 4 |
| SB590885 | C32 | 0.0032 | uM | 24 | hr | 2049 | 142 | 1.1026 | 1.0722 | 0.0693 | 0.0901 | 4 |
| SB590885 | C32 | 0.3160 | uM | 24 | hr | 2219 | 486 | 1.0020 | 0.9712 | 0.2190 | 0.2246 | 3 |
| SB590885 | C32 | 0.0032 | uM | 24 | hr | 2021 | 240 | 1.0297 | 1.0722 | 0.1188 | 0.0901 | 1 |
| SB590885 | C32 | 0.1000 | uM | 24 | hr | 2119 | 435 | 0.9736 | 1.0512 | 0.2053 | 0.1944 | 1 |
| SB590885 | C32 | 0.1000 | uM | 24 | hr | 2369 | 436 | 1.1176 | 1.0512 | 0.1840 | 0.1944 | 2 |
| SB590885 | C32 | 0.1000 | uM | 24 | hr | 2293 | 482 | 1.0470 | 1.0512 | 0.2102 | 0.1944 | 3 |
| SB590885 | C32 | 0.1000 | uM | 24 | hr | 2245 | 400 | 1.0667 | 1.0512 | 0.1782 | 0.1944 | 4 |
| SB590885 | C32 | 0.0032 | uM | 24 | hr | 2026 | 185 | 1.0644 | 1.0722 | 0.0913 | 0.0901 | 2 |
| PLX-4720 | C32 | 0.0100 | uM | 24 | hr | 1893 | 277 | 0.9343 | 1.0031 | 0.1463 | 0.1207 | 1 |
| PLX-4720 | C32 | 0.0100 | uM | 24 | hr | 2014 | 222 | 1.0361 | 1.0031 | 0.1102 | 0.1207 | 2 |
| SB590885 | C32 | 1.0000 | uM | 24 | hr | 1969 | 511 | 0.8430 | 0.8421 | 0.2595 | 0.2404 | 4 |
| SB590885 | C32 | 0.3160 | uM | 24 | hr | 2074 | 533 | 0.8909 | 0.9712 | 0.2570 | 0.2246 | 2 |
| SB590885 | C32 | 1.0000 | uM | 24 | hr | 1866 | 424 | 0.8337 | 0.8421 | 0.2272 | 0.2404 | 1 |
| SB590885 | C32 | 1.0000 | uM | 24 | hr | 1995 | 454 | 0.8909 | 0.8421 | 0.2276 | 0.2404 | 2 |
| SB590885 | C32 | 0.0032 | uM | 24 | hr | 2056 | 167 | 1.0921 | 1.0722 | 0.0812 | 0.0901 | 3 |
| SB590885 | C32 | 0.3160 | uM | 24 | hr | 2148 | 462 | 0.9748 | 0.9712 | 0.2151 | 0.2246 | 1 |
| PLX-4720 | C32 | 1.0000 | uM | 24 | hr | 1949 | 537 | 0.8164 | 0.8236 | 0.2755 | 0.2452 | 2 |
| PLX-4720 | C32 | 1.0000 | uM | 24 | hr | 1929 | 469 | 0.8441 | 0.8236 | 0.2431 | 0.2452 | 1 |