Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | WM1552C | 0.0032 | uM | 72 | hr | 6124 | 526 | 1.0858 | 1.0327 | 0.0859 | 0.0862 | 1 |
| AZ-628 | COLO 858 | 0.0100 | uM | 24 | hr | 4664 | 182 | 1.4972 | 1.1247 | 0.0390 | 0.0403 | 1 |
| SB590885 | WM1552C | 0.0316 | uM | 24 | hr | 2763 | 175 | 1.0329 | 0.9862 | 0.0633 | 0.0561 | 1 |
| SB590885 | COLO 858 | 0.0032 | uM | 24 | hr | 3566 | 150 | 1.1411 | 0.8658 | 0.0421 | 0.0451 | 1 |
| Selumetinib | C32 | 0.0032 | uM | 24 | hr | 1974 | 125 | 1.0690 | 1.0228 | 0.0633 | 0.0878 | 1 |
| AZ-628 | COLO 858 | 0.0100 | uM | 72 | hr | 3654 | 233 | 1.2426 | 1.1286 | 0.0638 | 0.0691 | 1 |
| SB590885 | RVH-421 | 0.0316 | uM | 24 | hr | 1551 | 65 | 1.0750 | 1.0352 | 0.0419 | 0.0478 | 1 |
| SB590885 | COLO 858 | 0.0032 | uM | 48 | hr | 4384 | 248 | 0.9450 | 0.9633 | 0.0566 | 0.0512 | 1 |
| SB590885 | WM1552C | 0.1000 | uM | 48 | hr | 3392 | 202 | 1.0147 | 0.9940 | 0.0596 | 0.0670 | 1 |
| SB590885 | WM1552C | 0.1000 | uM | 72 | hr | 6009 | 402 | 1.0876 | 1.0281 | 0.0669 | 0.0654 | 1 |
| SB590885 | C32 | 0.0032 | uM | 24 | hr | 2021 | 240 | 1.0297 | 1.0722 | 0.1188 | 0.0901 | 1 |
| SB590885 | COLO 858 | 0.0032 | uM | 72 | hr | 2877 | 269 | 0.9473 | 1.0703 | 0.0935 | 0.0855 | 1 |
| Selumetinib | C32 | 0.0032 | uM | 48 | hr | 2386 | 210 | 1.0588 | 1.2397 | 0.0880 | 0.0773 | 1 |
| SB590885 | COLO 858 | 0.0316 | uM | 24 | hr | 4716 | 182 | 1.5145 | 1.1972 | 0.0386 | 0.0423 | 1 |
| PLX-4720 | C32 | 0.1000 | uM | 72 | hr | 2073 | 69 | 0.8750 | 0.9374 | 0.0333 | 0.0354 | 1 |
| SB590885 | COLO 858 | 0.0100 | uM | 24 | hr | 4351 | 191 | 1.3896 | 1.2055 | 0.0439 | 0.0421 | 1 |
| SB590885 | RVH-421 | 0.1000 | uM | 48 | hr | 1116 | 69 | 0.5471 | 0.6891 | 0.0618 | 0.0578 | 1 |
| SB590885 | COLO 858 | 0.0100 | uM | 72 | hr | 3751 | 230 | 1.2789 | 1.2116 | 0.0613 | 0.0692 | 1 |
| SB590885 | C32 | 1.0000 | uM | 48 | hr | 1752 | 701 | 0.5114 | 0.5507 | 0.4001 | 0.3802 | 1 |
| SB590885 | COLO 858 | 0.0100 | uM | 48 | hr | 5029 | 267 | 1.0880 | 1.0343 | 0.0531 | 0.0508 | 1 |
| Selumetinib | C32 | 0.0032 | uM | 72 | hr | 1708 | 247 | 0.6379 | 0.8911 | 0.1446 | 0.1032 | 1 |
| SB590885 | COLO 858 | 0.0316 | uM | 48 | hr | 4147 | 201 | 0.9016 | 0.9293 | 0.0485 | 0.0484 | 1 |
| AZ-628 | COLO 858 | 0.0316 | uM | 72 | hr | 2304 | 149 | 0.7828 | 0.7158 | 0.0647 | 0.0679 | 1 |
| SB590885 | WM1552C | 3.1600 | uM | 72 | hr | 3930 | 413 | 0.6822 | 0.6158 | 0.1051 | 0.1127 | 1 |
| SB590885 | WM1552C | 3.1600 | uM | 48 | hr | 2776 | 149 | 0.8357 | 0.8203 | 0.0537 | 0.0655 | 1 |