Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
SB590885 LOXIMVI 0.0316
uM
 24
hr
 2182 87 0.8555 1.0209 0.0399 0.0361 4
PLX-4720 COLO 858 0.1000
uM
 72
hr
 2940 133 1.0196 0.8933 0.0452 0.0530 4
AZ-628 MZ7-mel 1.0000
uM
 72
hr
 1454 398 0.4399 0.3558 0.2737 0.2647 4
SB590885 LOXIMVI 0.0100
uM
 72
hr
 3530 1.6208 1.5053 0.2377 0.1880 4
SB590885 LOXIMVI 0.0100
uM
 48
hr
 2213 1.3386 1.3982 0.1003 0.0806 4
PLX-4720 C32 1.0000
uM
 48
hr
 1866 818 0.5099 0.4542 0.4384 0.4653 4
AZ-628 MZ7-mel 3.1600
uM
 24
hr
 875 51 0.6242 0.8782 0.0583 0.0453 4
SB590885 LOXIMVI 0.0100
uM
 24
hr
 2210 63 0.8768 1.0089 0.0285 0.0390 4
SB590885 LOXIMVI 0.0032
uM
 72
hr
 3167 1.2595 1.2376 0.3398 0.2526 4
AZ-628 SKMEL28 0.0100
uM
 48
hr
 2399 59 1.3937 1.4031 0.0246 0.0326 4
AZ-628 MZ7-mel 3.1600
uM
 48
hr
 1441 93 0.4173 0.4646 0.0645 0.0749 4
SB590885 LOXIMVI 0.0032
uM
 48
hr
 1461 0.7194 0.9624 0.2676 0.1426 4
SB590885 LOXIMVI 0.0032
uM
 24
hr
 2255 106 0.8776 0.9355 0.0470 0.0512 4
PLX-4720 COLO 858 0.1000
uM
 48
hr
 4361 214 0.9475 0.8929 0.0491 0.0498 4
AZ-628 MZ7-mel 3.1600
uM
 72
hr
 1240 382 0.3574 0.3266 0.3081 0.2930 4