Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | C32 | 0.0032 | uM | 48 | hr | 2479 | 281 | 1.0695 | 1.1088 | 0.1134 | 0.0967 | 1 |
| AZ-628 | C32 | 0.0032 | uM | 24 | hr | 2282 | 195 | 1.2066 | 1.0868 | 0.0855 | 0.0886 | 1 |
| SB590885 | C32 | 0.0316 | uM | 48 | hr | 2123 | 217 | 0.9274 | 1.0348 | 0.1022 | 0.0893 | 1 |
| PLX-4720 | C32 | 0.0032 | uM | 72 | hr | 2292 | 171 | 0.9260 | 0.9573 | 0.0746 | 0.0846 | 1 |
| AZ-628 | C32 | 0.0032 | uM | 72 | hr | 1962 | 179 | 0.7785 | 0.9919 | 0.0912 | 0.0829 | 1 |
| SB590885 | C32 | 0.0032 | uM | 24 | hr | 2021 | 240 | 1.0297 | 1.0722 | 0.1188 | 0.0901 | 1 |
| SB590885 | C32 | 0.0316 | uM | 72 | hr | 2637 | 79 | 1.1168 | 1.0834 | 0.0300 | 0.0299 | 1 |
| SB590885 | C32 | 0.0100 | uM | 48 | hr | 2014 | 286 | 0.8408 | 1.0390 | 0.1420 | 0.1215 | 1 |
| SB590885 | C32 | 3.1600 | uM | 24 | hr | 1858 | 507 | 0.7811 | 0.7788 | 0.2729 | 0.2708 | 1 |
| SB590885 | C32 | 0.0032 | uM | 72 | hr | 2185 | 204 | 0.8649 | 1.0978 | 0.0934 | 0.0657 | 1 |
| SB590885 | C32 | 0.1000 | uM | 24 | hr | 2119 | 435 | 0.9736 | 1.0512 | 0.2053 | 0.1944 | 1 |
| SB590885 | C32 | 1.0000 | uM | 72 | hr | 1164 | 580 | 0.2550 | 0.2758 | 0.4983 | 0.4735 | 1 |
| SB590885 | C32 | 0.0316 | uM | 24 | hr | 2141 | 401 | 1.0060 | 1.0901 | 0.1873 | 0.1588 | 1 |
| SB590885 | C32 | 0.0032 | uM | 48 | hr | 2306 | 278 | 0.9868 | 1.2035 | 0.1206 | 0.0832 | 1 |
| SB590885 | C32 | 0.1000 | uM | 48 | hr | 2176 | 195 | 0.9639 | 1.0641 | 0.0896 | 0.0770 | 1 |
| SB590885 | C32 | 0.0100 | uM | 72 | hr | 2781 | 198 | 1.1277 | 1.1912 | 0.0712 | 0.0532 | 1 |
| PLX-4720 | C32 | 0.0316 | uM | 72 | hr | 2777 | 157 | 1.1439 | 1.0994 | 0.0565 | 0.0684 | 1 |
| SB590885 | C32 | 0.3160 | uM | 72 | hr | 1227 | 361 | 0.3781 | 0.4360 | 0.2942 | 0.2745 | 1 |
| SB590885 | C32 | 0.1000 | uM | 72 | hr | 1770 | 127 | 0.7173 | 0.7616 | 0.0718 | 0.0807 | 1 |
| PLX-4720 | C32 | 0.1000 | uM | 72 | hr | 2073 | 69 | 0.8750 | 0.9374 | 0.0333 | 0.0354 | 1 |
| PLX-4720 | C32 | 0.3160 | uM | 24 | hr | 1973 | 326 | 0.9522 | 0.9421 | 0.1652 | 0.1737 | 1 |
| SB590885 | C32 | 1.0000 | uM | 24 | hr | 1866 | 424 | 0.8337 | 0.8421 | 0.2272 | 0.2404 | 1 |
| SB590885 | C32 | 0.3160 | uM | 24 | hr | 2148 | 462 | 0.9748 | 0.9712 | 0.2151 | 0.2246 | 1 |
| AZ-628 | C32 | 0.0316 | uM | 48 | hr | 2095 | 191 | 0.9264 | 1.0132 | 0.0912 | 0.0851 | 1 |
| AZ-628 | C32 | 0.0316 | uM | 24 | hr | 2275 | 387 | 1.0916 | 1.0452 | 0.1701 | 0.1770 | 1 |