Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Selumetinib | LOXIMVI | 0.0316 | uM | 48 | hr | 1874 | 1.1900 | 1.2038 | 0.0555 | 0.0621 | 4 | |
| AZ-628 | K2 | 0.3160 | uM | 72 | hr | 1 | ||||||
| AZ-628 | K2 | 0.3160 | uM | 72 | hr | 2 | ||||||
| AZ-628 | K2 | 0.3160 | uM | 72 | hr | 3 | ||||||
| AZ-628 | K2 | 0.3160 | uM | 72 | hr | 4 | ||||||
| Selumetinib | LOXIMVI | 0.0316 | uM | 48 | hr | 1628 | 1.0320 | 1.2038 | 0.0571 | 0.0621 | 3 | |
| Selumetinib | LOXIMVI | 0.0316 | uM | 48 | hr | 2605 | 1.6519 | 1.2038 | 0.0568 | 0.0621 | 2 | |
| Selumetinib | LOXIMVI | 0.0316 | uM | 48 | hr | 1520 | 0.9412 | 1.2038 | 0.0789 | 0.0621 | 1 | |
| SB590885 | WM1552C | 0.1000 | uM | 24 | hr | 4 | ||||||
| Selumetinib | LOXIMVI | 0.0100 | uM | 72 | hr | 4625 | 2.5737 | 1.9337 | 0.0761 | 0.0676 | 4 | |
| AZ-628 | K2 | 1.0000 | uM | 72 | hr | 1 | ||||||
| AZ-628 | K2 | 1.0000 | uM | 72 | hr | 2 | ||||||
| AZ-628 | K2 | 1.0000 | uM | 72 | hr | 3 | ||||||
| AZ-628 | K2 | 1.0000 | uM | 72 | hr | 4 | ||||||
| Selumetinib | LOXIMVI | 0.0100 | uM | 72 | hr | 2764 | 1.5552 | 1.9337 | 0.0658 | 0.0676 | 3 |