Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | K2 | 0.1000 | uM | 24 | hr | 4354 | 8 | 2.5560 | 2.0680 | 0.0018 | 0.0026 | 2 |
| AZ-628 | K2 | 0.0032 | uM | 48 | hr | 3471 | 14 | 1.2616 | 1.1976 | 0.0040 | 0.0026 | 4 |
| AZ-628 | K2 | 0.0032 | uM | 48 | hr | 3396 | 5 | 1.2375 | 1.1976 | 0.0015 | 0.0026 | 2 |
| Vemurafenib | K2 | 0.0100 | uM | 48 | hr | 4070 | 6 | 1.4831 | 1.3424 | 0.0015 | 0.0026 | 3 |
| Vemurafenib | K2 | 0.0100 | uM | 48 | hr | 3320 | 15 | 1.2061 | 1.3424 | 0.0045 | 0.0026 | 2 |
| Vemurafenib | K2 | 0.0100 | uM | 48 | hr | 3397 | 6 | 1.2375 | 1.3424 | 0.0018 | 0.0026 | 1 |
| SB590885 | K2 | 0.1000 | uM | 24 | hr | 3687 | 11 | 2.1620 | 2.0680 | 0.0030 | 0.0026 | 1 |
| AZ-628 | K2 | 0.0032 | uM | 48 | hr | 3006 | 9 | 1.0937 | 1.1976 | 0.0030 | 0.0026 | 3 |
| SB590885 | K2 | 0.1000 | uM | 24 | hr | 3414 | 8 | 2.0032 | 2.0680 | 0.0023 | 0.0026 | 4 |
| Vemurafenib | K2 | 0.0100 | uM | 48 | hr | 3964 | 10 | 1.4430 | 1.3424 | 0.0025 | 0.0026 | 4 |
| Selumetinib | K2 | 0.0032 | uM | 48 | hr | 3226 | 9 | 1.1740 | 1.1652 | 0.0028 | 0.0027 | 4 |
| Selumetinib | K2 | 0.0032 | uM | 48 | hr | 3572 | 7 | 1.3010 | 1.1652 | 0.0020 | 0.0027 | 1 |
| Selumetinib | K2 | 0.0032 | uM | 48 | hr | 2629 | 12 | 0.9551 | 1.1652 | 0.0046 | 0.0027 | 3 |
| Selumetinib | K2 | 0.0032 | uM | 48 | hr | 3377 | 5 | 1.2306 | 1.1652 | 0.0015 | 0.0027 | 2 |
| SB590885 | K2 | 0.0100 | uM | 48 | hr | 3901 | 6 | 1.4215 | 1.3746 | 0.0015 | 0.0028 | 1 |
| AZ-628 | K2 | 0.0316 | uM | 24 | hr | 3562 | 11 | 2.0884 | 1.5718 | 0.0031 | 0.0028 | 2 |
| AZ-628 | K2 | 0.0316 | uM | 24 | hr | 3254 | 3 | 1.9120 | 1.5718 | 0.0009 | 0.0028 | 1 |
| AZ-628 | K2 | 0.0316 | uM | 24 | hr | 1886 | 3 | 1.1074 | 1.5718 | 0.0016 | 0.0028 | 3 |
| SB590885 | K2 | 0.0100 | uM | 48 | hr | 3833 | 12 | 1.3944 | 1.3746 | 0.0031 | 0.0028 | 3 |
| SB590885 | K2 | 0.0100 | uM | 48 | hr | 4044 | 15 | 1.4704 | 1.3746 | 0.0037 | 0.0028 | 4 |
| SB590885 | K2 | 0.0100 | uM | 48 | hr | 3332 | 10 | 1.2123 | 1.3746 | 0.0030 | 0.0028 | 2 |
| AZ-628 | K2 | 0.0316 | uM | 24 | hr | 2016 | 11 | 1.1792 | 1.5718 | 0.0055 | 0.0028 | 4 |
| AZ-628 | K2 | 0.0100 | uM | 24 | hr | 2893 | 9 | 1.6962 | 1.4274 | 0.0031 | 0.0030 | 1 |
| AZ-628 | K2 | 0.0100 | uM | 48 | hr | 2821 | 10 | 1.0259 | 1.0336 | 0.0035 | 0.0030 | 3 |
| AZ-628 | K2 | 0.0100 | uM | 48 | hr | 2909 | 7 | 1.0591 | 1.0336 | 0.0024 | 0.0030 | 4 |