Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | K2 | 0.0100 | uM | 48 | hr | 3702 | 8 | 1.3481 | 1.2705 | 0.0022 | 0.0022 | 3 |
| SB590885 | K2 | 0.0316 | uM | 24 | hr | 2744 | 8 | 1.6091 | 1.8176 | 0.0029 | 0.0022 | 4 |
| SB590885 | K2 | 0.0316 | uM | 24 | hr | 2387 | 4 | 1.4015 | 1.8176 | 0.0017 | 0.0022 | 3 |
| Vemurafenib | K2 | 0.1000 | uM | 48 | hr | 3765 | 6 | 1.3718 | 1.4312 | 0.0016 | 0.0023 | 4 |
| Vemurafenib | K2 | 0.1000 | uM | 48 | hr | 4523 | 16 | 1.6448 | 1.4312 | 0.0035 | 0.0023 | 3 |
| Vemurafenib | K2 | 0.1000 | uM | 48 | hr | 3718 | 5 | 1.3550 | 1.4312 | 0.0013 | 0.0023 | 1 |
| Vemurafenib | K2 | 0.1000 | uM | 48 | hr | 3718 | 10 | 1.3532 | 1.4312 | 0.0027 | 0.0023 | 2 |
| Vemurafenib | K2 | 0.0100 | uM | 24 | hr | 4147 | 7 | 2.4348 | 2.0827 | 0.0017 | 0.0023 | 2 |
| Vemurafenib | K2 | 0.0100 | uM | 24 | hr | 2792 | 8 | 1.6373 | 2.0827 | 0.0029 | 0.0023 | 3 |
| Vemurafenib | K2 | 0.0100 | uM | 24 | hr | 4217 | 9 | 2.4748 | 2.0827 | 0.0021 | 0.0023 | 1 |
| Vemurafenib | K2 | 0.0100 | uM | 24 | hr | 3041 | 8 | 1.7838 | 2.0827 | 0.0026 | 0.0023 | 4 |
| SB590885 | K2 | 0.0100 | uM | 24 | hr | 2384 | 8 | 1.3974 | 1.7957 | 0.0034 | 0.0024 | 3 |
| SB590885 | K2 | 0.0100 | uM | 24 | hr | 3664 | 5 | 2.1520 | 1.7957 | 0.0014 | 0.0024 | 1 |
| SB590885 | K2 | 0.0100 | uM | 24 | hr | 3633 | 7 | 2.1325 | 1.7957 | 0.0019 | 0.0024 | 2 |
| PLX-4720 | K2 | 0.0032 | uM | 48 | hr | 3223 | 7 | 1.1737 | 1.3444 | 0.0022 | 0.0024 | 2 |
| SB590885 | K2 | 0.0100 | uM | 24 | hr | 2560 | 8 | 1.5009 | 1.7957 | 0.0031 | 0.0024 | 4 |
| PLX-4720 | K2 | 0.0032 | uM | 48 | hr | 4064 | 15 | 1.4777 | 1.3444 | 0.0037 | 0.0024 | 3 |
| PLX-4720 | K2 | 0.0032 | uM | 48 | hr | 3865 | 1 | 1.4101 | 1.3444 | 0.0003 | 0.0024 | 1 |
| PLX-4720 | K2 | 0.0032 | uM | 48 | hr | 3619 | 12 | 1.3163 | 1.3444 | 0.0033 | 0.0024 | 4 |
| Vemurafenib | K2 | 0.0100 | uM | 48 | hr | 3320 | 15 | 1.2061 | 1.3424 | 0.0045 | 0.0026 | 2 |
| Vemurafenib | K2 | 0.0100 | uM | 48 | hr | 4070 | 6 | 1.4831 | 1.3424 | 0.0015 | 0.0026 | 3 |
| Vemurafenib | K2 | 0.0316 | uM | 24 | hr | 2959 | 5 | 1.7373 | 2.1662 | 0.0017 | 0.0026 | 3 |
| SB590885 | K2 | 0.1000 | uM | 24 | hr | 3414 | 8 | 2.0032 | 2.0680 | 0.0023 | 0.0026 | 4 |
| Vemurafenib | K2 | 0.0100 | uM | 48 | hr | 3964 | 10 | 1.4430 | 1.3424 | 0.0025 | 0.0026 | 4 |
| Vemurafenib | K2 | 0.0316 | uM | 24 | hr | 4239 | 7 | 2.4890 | 2.1662 | 0.0017 | 0.0026 | 1 |