Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | MZ7-mel | 3.1600 | uM | 24 | hr | 1193 | 44 | 0.8705 | 0.7951 | 0.0369 | 0.0325 | 1 |
| PLX-4720 | MZ7-mel | 3.1600 | uM | 24 | hr | 1193 | 28 | 0.8826 | 0.7951 | 0.0235 | 0.0325 | 2 |
| PLX-4720 | MZ7-mel | 3.1600 | uM | 24 | hr | 857 | 36 | 0.6220 | 0.7951 | 0.0420 | 0.0325 | 3 |
| PLX-4720 | MZ7-mel | 3.1600 | uM | 24 | hr | 1093 | 30 | 0.8053 | 0.7951 | 0.0274 | 0.0325 | 4 |
| PLX-4720 | MZ7-mel | 3.1600 | uM | 48 | hr | 1655 | 70 | 0.4907 | 0.4803 | 0.0423 | 0.0483 | 1 |
| PLX-4720 | MZ7-mel | 3.1600 | uM | 48 | hr | 1663 | 69 | 0.4935 | 0.4803 | 0.0415 | 0.0483 | 2 |
| PLX-4720 | MZ7-mel | 3.1600 | uM | 48 | hr | 1612 | 84 | 0.4731 | 0.4803 | 0.0521 | 0.0483 | 3 |
| PLX-4720 | MZ7-mel | 3.1600 | uM | 48 | hr | 1589 | 91 | 0.4638 | 0.4803 | 0.0573 | 0.0483 | 4 |
| PLX-4720 | WM1552C | 3.1600 | uM | 72 | hr | 2791 | 355 | 0.4725 | 0.4966 | 0.1272 | 0.1295 | 4 |
| PLX-4720 | WM1552C | 3.1600 | uM | 72 | hr | 2644 | 325 | 0.4498 | 0.4966 | 0.1229 | 0.1295 | 3 |
| PLX-4720 | WM1552C | 3.1600 | uM | 72 | hr | 3028 | 426 | 0.5047 | 0.4966 | 0.1407 | 0.1295 | 2 |
| PLX-4720 | WM1552C | 3.1600 | uM | 72 | hr | 3305 | 420 | 0.5596 | 0.4966 | 0.1271 | 0.1295 | 1 |
| PLX-4720 | WM1552C | 3.1600 | uM | 48 | hr | 2432 | 215 | 0.7052 | 0.7234 | 0.0884 | 0.0762 | 4 |
| PLX-4720 | WM1552C | 3.1600 | uM | 48 | hr | 2431 | 242 | 0.6963 | 0.7234 | 0.0995 | 0.0762 | 3 |
| PLX-4720 | WM1552C | 3.1600 | uM | 48 | hr | 2469 | 143 | 0.7399 | 0.7234 | 0.0579 | 0.0762 | 2 |