Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
AZ-628 K2 0.0316
uM
 24
hr
 1886 3 1.1074 1.5718 0.0016 0.0028 3
K2 0.0000
uM
 48
hr
 3119 5 1.1364 0.0016 3
Vemurafenib K2 0.0032
uM
 48
hr
 3821 6 1.3923 1.4412 0.0016 0.0031 1
Vemurafenib K2 0.1000
uM
 48
hr
 3765 6 1.3718 1.4312 0.0016 0.0023 4
Vemurafenib K2 0.1000
uM
 24
hr
 3143 5 1.8455 2.1002 0.0016 0.0017 3
Vemurafenib K2 0.0100
uM
 24
hr
 4147 7 2.4348 2.0827 0.0017 0.0023 2
SB590885 K2 0.0316
uM
 48
hr
 3564 6 1.2985 1.3782 0.0017 0.0017 2
Vemurafenib K2 0.0316
uM
 24
hr
 4239 7 2.4890 2.1662 0.0017 0.0026 1
SB590885 K2 0.0032
uM
 48
hr
 4588 8 1.6714 1.5110 0.0017 0.0019 4
SB590885 K2 0.0316
uM
 24
hr
 2387 4 1.4015 1.8176 0.0017 0.0022 3
Vemurafenib K2 0.0316
uM
 24
hr
 2959 5 1.7373 2.1662 0.0017 0.0026 3
SB590885 K2 0.1000
uM
 24
hr
 4354 8 2.5560 2.0680 0.0018 0.0026 2
K2 0.0000
uM
 48
hr
 4326 8 1.5758 0.0018 1
SB590885 K2 0.0032
uM
 48
hr
 3865 7 1.4079 1.5110 0.0018 0.0019 1
AZ-628 K2 0.0032
uM
 48
hr
 3287 6 1.1974 1.1976 0.0018 0.0026 1
K2 0.0000
uM
 24
hr
 2794 5 1.6403 0.0018 1
Vemurafenib K2 0.0100
uM
 48
hr
 3397 6 1.2375 1.3424 0.0018 0.0026 1
Vemurafenib K2 0.0316
uM
 48
hr
 3964 7 1.4441 1.3791 0.0018 0.0017 2
AZ-628 MZ7-mel 0.1000
uM
 24
hr
 1651 3 1.2485 1.1884 0.0018 0.0081 1
K2 0.0000
uM
 24
hr
 3904 7 2.2919 0.0018 2
Vemurafenib K2 0.0316
uM
 48
hr
 3651 7 1.3299 1.3791 0.0019 0.0017 4
PLX-4720 K2 0.0316
uM
 48
hr
 3231 6 1.1769 1.1865 0.0019 0.0020 1
SB590885 K2 0.0100
uM
 24
hr
 3633 7 2.1325 1.7957 0.0019 0.0024 2
K2 0.0000
uM
 48
hr
 3017 6 1.0988 0.0020 2
Vemurafenib K2 0.0316
uM
 48
hr
 3560 7 1.2966 1.3791 0.0020 0.0017 1