Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | RVH-421 | 0.0100 | uM | 72 | hr | 9239 | 359 | 1.0176 | 1.0312 | 0.0389 | 0.0350 | 1 |
| RVH-421 | 0.0000 | uM | 72 | hr | 9231 | 298 | 1.0236 | 0.0323 | 2 | |||
| Vemurafenib | RVH-421 | 0.0316 | uM | 72 | hr | 9218 | 329 | 1.0186 | 0.9594 | 0.0357 | 0.0341 | 2 |
| RVH-421 | 0.0000 | uM | 72 | hr | 9200 | 327 | 1.0168 | 0.0355 | 2 | |||
| PLX-4720 | RVH-421 | 0.0316 | uM | 72 | hr | 9190 | 336 | 1.0146 | 1.0084 | 0.0366 | 0.0338 | 1 |
| RVH-421 | 0.0000 | uM | 72 | hr | 9171 | 300 | 1.0165 | 0.0327 | 1 | |||
| SB590885 | RVH-421 | 0.0100 | uM | 72 | hr | 9170 | 340 | 1.0118 | 0.9950 | 0.0371 | 0.0346 | 2 |
| RVH-421 | 0.0000 | uM | 72 | hr | 9150 | 403 | 1.0023 | 0.0440 | 3 | |||
| SB590885 | RVH-421 | 0.0100 | uM | 72 | hr | 9138 | 304 | 1.0123 | 0.9950 | 0.0333 | 0.0346 | 4 |
| Vemurafenib | RVH-421 | 0.0100 | uM | 72 | hr | 9119 | 274 | 1.0135 | 1.0156 | 0.0300 | 0.0343 | 3 |
| RVH-421 | 0.0000 | uM | 72 | hr | 9109 | 324 | 1.0067 | 0.0356 | 2 | |||
| PLX-4720 | RVH-421 | 0.0100 | uM | 72 | hr | 9105 | 306 | 1.0083 | 1.0312 | 0.0336 | 0.0350 | 3 |
| PLX-4720 | RVH-421 | 0.0032 | uM | 72 | hr | 9097 | 299 | 1.0082 | 0.9785 | 0.0329 | 0.0342 | 4 |
| Selumetinib | RVH-421 | 0.0316 | uM | 72 | hr | 9042 | 260 | 1.0063 | 0.8489 | 0.0288 | 0.0318 | 2 |
| PLX-4720 | RVH-421 | 0.0316 | uM | 72 | hr | 9001 | 259 | 1.0017 | 1.0084 | 0.0288 | 0.0338 | 4 |
| RVH-421 | 0.0000 | uM | 72 | hr | 8969 | 339 | 0.9889 | 0.0378 | 2 | |||
| PLX-4720 | RVH-421 | 0.0032 | uM | 72 | hr | 8953 | 309 | 0.9905 | 0.9785 | 0.0345 | 0.0342 | 3 |
| SB590885 | RVH-421 | 0.0032 | uM | 72 | hr | 8943 | 321 | 0.9880 | 0.9834 | 0.0359 | 0.0342 | 1 |
| PLX-4720 | RVH-421 | 0.0032 | uM | 72 | hr | 8938 | 335 | 0.9858 | 0.9785 | 0.0375 | 0.0342 | 2 |
| AZ-628 | RVH-421 | 0.0100 | uM | 72 | hr | 8925 | 283 | 0.9903 | 0.9153 | 0.0317 | 0.0320 | 2 |
| SB590885 | RVH-421 | 0.0100 | uM | 72 | hr | 8907 | 294 | 0.9870 | 0.9950 | 0.0330 | 0.0346 | 3 |
| Selumetinib | RVH-421 | 0.0100 | uM | 72 | hr | 8900 | 313 | 0.9840 | 0.9881 | 0.0352 | 0.0321 | 4 |
| Selumetinib | RVH-421 | 0.0100 | uM | 72 | hr | 8827 | 231 | 0.9850 | 0.9881 | 0.0262 | 0.0321 | 1 |
| Vemurafenib | RVH-421 | 0.1000 | uM | 72 | hr | 8801 | 279 | 0.9765 | 0.9093 | 0.0317 | 0.0335 | 1 |
| SB590885 | RVH-421 | 0.0032 | uM | 72 | hr | 8799 | 286 | 0.9755 | 0.9834 | 0.0325 | 0.0342 | 3 |