Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
AZ-628 SKMEL28 1.0000
uM
 72
hr
 756 77 0.5093 0.4893 0.1019 0.1068 4
AZ-628 SKMEL28 3.1600
uM
 24
hr
 1
AZ-628 SKMEL28 3.1600
uM
 24
hr
 2
AZ-628 SKMEL28 3.1600
uM
 24
hr
 3
AZ-628 SKMEL28 3.1600
uM
 24
hr
 4
AZ-628 SKMEL28 3.1600
uM
 48
hr
 1094 94 0.5956 0.6142 0.0859 0.0900 1
AZ-628 SKMEL28 3.1600
uM
 48
hr
 1166 118 0.6242 0.6142 0.1012 0.0900 2
AZ-628 SKMEL28 3.1600
uM
 48
hr
 1159 109 0.6254 0.6142 0.0940 0.0900 3
AZ-628 SKMEL28 3.1600
uM
 48
hr
 1115 88 0.6117 0.6142 0.0789 0.0900 4
AZ-628 SKMEL28 3.1600
uM
 72
hr
 663 99 0.4231 0.4420 0.1493 0.1421 1
AZ-628 SKMEL28 3.1600
uM
 72
hr
 746 100 0.4846 0.4420 0.1341 0.1421 2
AZ-628 SKMEL28 3.1600
uM
 72
hr
 728 100 0.4711 0.4420 0.1374 0.1421 3
AZ-628 SKMEL28 3.1600
uM
 72
hr
 609 90 0.3893 0.4420 0.1478 0.1421 4
Selumetinib SKMEL28 0.0032
uM
 24
hr
 1
Selumetinib SKMEL28 0.0032
uM
 24
hr
 2
Selumetinib SKMEL28 0.0032
uM
 24
hr
 3
Selumetinib SKMEL28 0.0032
uM
 24
hr
 4
Selumetinib SKMEL28 0.0032
uM
 48
hr
 1228 44 0.7052 0.7990 0.0358 0.0348 1
Selumetinib SKMEL28 0.0032
uM
 48
hr
 1212 41 0.6975 0.7990 0.0338 0.0348 2
Selumetinib SKMEL28 0.0032
uM
 48
hr
 1616 52 0.9315 0.7990 0.0322 0.0348 3
Selumetinib SKMEL28 0.0032
uM
 48
hr
 1503 56 0.8618 0.7990 0.0373 0.0348 4
Selumetinib SKMEL28 0.0032
uM
 72
hr
 1372 46 0.9947 1.0562 0.0335 0.0360 1
Selumetinib SKMEL28 0.0032
uM
 72
hr
 1517 46 1.1034 1.0562 0.0303 0.0360 2
Selumetinib SKMEL28 0.0032
uM
 72
hr
 1229 55 0.8806 1.0562 0.0448 0.0360 3
Selumetinib SKMEL28 0.0032
uM
 72
hr
 1722 61 1.2459 1.0562 0.0354 0.0360 4