Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| MK2206 | T47D | 10.0 | uM | 24 | hr | 183.08 | 52.93 | p-S6 | 33.32 | |
| Dactolisib | HCC1954 | 3.16 | nM | 24 | hr | 321.07 | 124.41 | p-S6 | 414.54 | |
| Triciribine | T47D | 10.0 | uM | 24 | hr | 195.69 | 74.52 | p-S6 | 435.43 | |
| Dactolisib | T47D | 31.6 | nM | 24 | hr | 128.11 | 59.27 | p-4EBP1 | 215.44 | |
| Dactolisib | T47D | 10.0 | uM | 24 | hr | 142.42 | 100.03 | p-S6 | 6.69 | |