Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Triciribine | MCF 10A | 316.0 | nM | 24 | hr | 297.79 | 145.81 | p-S6 | 300.11 | |
| Triciribine | T47D | 10.0 | uM | 6 | hr | 103.50 | 31.15 | p-4EBP1 | 87.59 | |
| Triciribine | T47D | 10.0 | uM | 24 | hr | 155.73 | 64.52 | p-4EBP1 | 343.55 | |
| Triciribine | HCC1954 | 1.0 | uM | 24 | hr | 216.58 | 102.83 | p-4EBP1 | 109.56 | |
| Triciribine | AU565 | 100.0 | nM | 6 | hr | 298.70 | 77.47 | p-S6 | 170.69 | |