Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Gefitinib | MCF 10A | 316.0 | nM | 24 | hr | 262.25 | 189.00 | p-S6 | 404.58 | |
| Gefitinib | MCF 10A | 31.6 | nM | 24 | hr | 408.64 | 195.12 | p-S6 | 597.71 | |
| Gefitinib | MCF 10A | 100.0 | nM | 24 | hr | 372.85 | 195.99 | p-S6 | 350.71 | |
| GSK1059615 | MCF 10A | 10.0 | nM | 6 | hr | 453.23 | 198.94 | p-S6 | 918.10 | |
| Gefitinib | MCF 10A | 100.0 | nM | 24 | hr | 416.72 | 200.10 | p-S6 | 651.75 | |