Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Torkinib | MCF 10A | 1.78 | nM | 6 | hr | 479.13 | 181.71 | p-S6 | 769.25 | |
| Torkinib | MCF 10A | 7.5 | nM | 6 | hr | 516.67 | 184.66 | p-S6 | 775.89 | |
| GSK1059615 | MCF 10A | 3.16 | nM | 6 | hr | 446.31 | 184.25 | p-S6 | 782.26 | |
| GSK1059615 | MCF 10A | 31.6 | nM | 6 | hr | 411.99 | 186.56 | p-S6 | 785.76 | |
| GSK1059615 | MCF 10A | 10.0 | nM | 6 | hr | 453.23 | 198.94 | p-S6 | 918.10 | |