Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Triciribine | HCC1954 | 0 (control) | 6 | hr | 242.63 | 86.72 | p-S6 | 308.51 | | |
| Triciribine | HCC1954 | 3.16 | nM | 6 | hr | 173.10 | 49.87 | p-4EBP1 | 76.11 | |
| Triciribine | HCC1954 | 1.0 | uM | 6 | hr | 262.74 | 87.39 | p-4EBP1 | 128.31 | |
| Triciribine | HCC1954 | 3.16 | nM | 6 | hr | 247.28 | 82.46 | p-Akt | 41.77 | |
| Triciribine | HCC1954 | 31.6 | nM | 6 | hr | 250.28 | 91.52 | p-4EBP1 | 117.60 | |