Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Torkinib | T47D | 7.5 | nM | 24 | hr | 135.75 | 78.36 | p-4EBP1 | 306.59 | |
| Torkinib | AU565 | 7.5 | nM | 24 | hr | 440.89 | 99.20 | p-4EBP1 | 147.59 | |
| Torkinib | T47D | 7.5 | nM | 24 | hr | 138.86 | 70.27 | p-Akt | 34.18 | |
| Torkinib | AU565 | 7.5 | nM | 6 | hr | 270.94 | 52.71 | p-Akt | 17.37 | |
| Torkinib | AU565 | 7.5 | nM | 24 | hr | 463.58 | 90.29 | p-Akt | 56.28 | |