Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Gefitinib | HCC1954 | 0 (control) | 24 | hr | 288.62 | 115.70 | p-Akt | 79.49 | | |
| Gefitinib | HCC1954 | 0 (control) | 6 | hr | 184.31 | 43.16 | p-Akt | 18.10 | | |
| Dactolisib | AU565 | 0 (control) | 24 | hr | 545.09 | 120.07 | p-Akt | 140.76 | | |
| Dactolisib | AU565 | 0 (control) | 6 | hr | 206.58 | 47.55 | p-Akt | 19.83 | | |
| Triciribine | AU565 | 0 (control) | 24 | hr | 526.07 | 122.68 | p-Akt | 106.24 | |