Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| MK2206 | T47D | 31.6 | nM | 24 | hr | 149.34 | 93.03 | p-4EBP1 | 348.95 | |
| Triciribine | T47D | 31.6 | nM | 6 | hr | 104.52 | 59.70 | p-4EBP1 | 189.42 | |
| Triciribine | T47D | 31.6 | nM | 24 | hr | 165.90 | 102.35 | p-4EBP1 | 358.91 | |
| Dactolisib | T47D | 31.6 | nM | 6 | hr | 78.85 | 35.77 | p-4EBP1 | 95.11 | |
| Dactolisib | T47D | 31.6 | nM | 24 | hr | 128.11 | 59.27 | p-4EBP1 | 215.44 | |