Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Torkinib | T47D | 10.0 | uM | 6 | hr | 161.35 | 70.83 | p-S6 | 6.32 | |
| GSK1059615 | T47D | 10.0 | uM | 6 | hr | 172.04 | 64.90 | p-S6 | 9.29 | |
| MK2206 | T47D | 10.0 | uM | 6 | hr | 132.61 | 47.26 | p-S6 | 58.99 | |
| Triciribine | T47D | 10.0 | uM | 6 | hr | 110.45 | 41.24 | p-S6 | 39.23 | |
| Dactolisib | T47D | 10.0 | uM | 6 | hr | 88.85 | 36.94 | p-S6 | 4.07 | |