Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Dactolisib | HCC1954 | 0 (control) | 6 | hr | 255.38 | 84.53 | p-4EBP1 | 99.75 | | |
| Dactolisib | AU565 | 0 (control) | 24 | hr | 508.92 | 132.23 | p-4EBP1 | 196.24 | | |
| Dactolisib | AU565 | 0 (control) | 6 | hr | 218.03 | 53.42 | p-4EBP1 | 64.33 | | |
| Dactolisib | T47D | 10.0 | uM | 6 | hr | 85.23 | 24.35 | p-4EBP1 | 5.42 | |
| Dactolisib | T47D | 10.0 | uM | 24 | hr | 134.86 | 101.30 | p-4EBP1 | 14.17 | |