Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Dactolisib | T47D | 31.6 | nM | 6 | hr | 84.81 | 35.55 | p-Akt | 8.51 | |
| Dactolisib | T47D | 100.0 | nM | 6 | hr | 84.56 | 34.41 | p-Akt | 6.52 | |
| Dactolisib | T47D | 100.0 | nM | 6 | hr | 80.72 | 30.01 | p-S6 | 3.74 | |
| Dactolisib | T47D | 31.6 | nM | 6 | hr | 78.85 | 35.77 | p-4EBP1 | 95.11 | |
| Dactolisib | T47D | 100.0 | nM | 6 | hr | 75.87 | 27.61 | p-4EBP1 | 41.17 | |