Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Torkinib | HCC1954 | 2.37 | uM | 6 | hr | 143.76 | 24.81 | p-S6 | 9.70 | |
| Gefitinib | MCF 10A | 3.16 | uM | 24 | hr | 173.69 | 24.68 | p-Akt | 20.53 | |
| Triciribine | T47D | 3.16 | uM | 6 | hr | 103.46 | 24.67 | p-Akt | 8.36 | |
| Dactolisib | T47D | 10.0 | uM | 6 | hr | 85.23 | 24.35 | p-4EBP1 | 5.42 | |
| Gefitinib | MCF 10A | 10.0 | uM | 24 | hr | 144.97 | 21.29 | p-Akt | 18.43 | |