Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Dactolisib | T47D | 10.0 | uM | 6 | hr | 85.91 | 37.58 | p-S6 | 3.98 | |
| Dactolisib | T47D | 316.0 | nM | 6 | hr | 91.80 | 41.44 | p-S6 | 3.90 | |
| Dactolisib | T47D | 1.0 | uM | 6 | hr | 93.77 | 37.06 | p-S6 | 3.89 | |
| Dactolisib | T47D | 1.0 | uM | 6 | hr | 89.72 | 38.09 | p-S6 | 3.89 | |
| Dactolisib | T47D | 100.0 | nM | 6 | hr | 80.72 | 30.01 | p-S6 | 3.74 | |