Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Gefitinib | AU565 | 10.0 | nM | 6 | hr | 241.48 | 51.68 | p-Akt | 25.73 | |
| Gefitinib | AU565 | 316.0 | nM | 6 | hr | 234.01 | 54.85 | p-Akt | 22.11 | |
| Gefitinib | AU565 | 316.0 | nM | 6 | hr | 289.30 | 66.48 | p-4EBP1 | 93.41 | |
| Gefitinib | AU565 | 316.0 | nM | 6 | hr | 228.71 | 57.03 | p-Akt | 21.72 | |
| Gefitinib | AU565 | 0 (control) | 6 | hr | 286.03 | 62.73 | p-Akt | 29.07 | |