Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| Torkinib | HCC1954 | 0.1 | nM | 24 | hr | 292.92 | 106.38 | p-Akt | 66.25 | |
| Torkinib | HCC1954 | 0.1 | nM | 6 | hr | 230.43 | 52.31 | p-S6 | 123.13 | |
| Torkinib | HCC1954 | 0.1 | nM | 24 | hr | 291.18 | 108.05 | p-S6 | 406.86 | |
| Torkinib | HCC1954 | 0.1 | nM | 6 | hr | 195.86 | 37.51 | p-Akt | 23.03 | |
| Torkinib | T47D | 0.1 | nM | 6 | hr | 176.07 | 94.03 | p-S6 | 481.17 | |