Breast cell line dose response to target inhibition measured by high throughput microscopy - Dataset (ID:20136)
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| Small Molecule | Cell Line | Drug Concentration | Conc Units | Timepoint | Timepoint Units | Measured pERK (Alexa 488) | Measured p-Rb (Alexa 568) | Alexa Fluor 647 | Measured p-Akt/p-4EBP1/p-S6 (Alexa 647) | Image |
|---|---|---|---|---|---|---|---|---|---|---|
| GSK1059615 | MCF 10A | 0 (control) | 6 | hr | 450.57 | 164.32 | p-Akt | 55.84 | | |
| Torkinib | MCF 10A | 0 (control) | 24 | hr | 335.16 | 114.92 | p-Akt | 54.49 | | |
| Torkinib | MCF 10A | 0 (control) | 6 | hr | 498.87 | 147.67 | p-Akt | 54.88 | | |
| Gefitinib | MCF 10A | 0 (control) | 24 | hr | 295.80 | 110.01 | p-Akt | 55.06 | | |
| Gefitinib | MCF 10A | 0 (control) | 6 | hr | 488.10 | 165.19 | p-Akt | 54.11 | |