XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| XMD-12 | PC-3 | CDK2 | DLkPQNLLINTEGAIK | Lys2 | -4.2 | 10 | uM |
| XMD-12 | HeLa | CDK2 | DLkPQNLLINTEGAIK | Lys2 | -11.3 | 10 | uM |
| XMD-12 | PC-3 | CDK5 | DLkPQNLLINR | Lys2 | 12.5 | 10 | uM |
| XMD-12 | PC-3 | CDK5 | NRETHEIVALkR | Lys1 | 2.4 | 10 | uM |
| XMD-12 | PC-3 | CDK5 | ETHEIVALkR | Lys1 | 4.5 | 10 | uM |
| XMD-12 | HeLa | CDK7 | DLkPNNLLLDENGVLK | Lys2 | 62.7 | 10 | uM |
| XMD-12 | PC-3 | CDK9 | DMkAANVLITR | Lys2 | 14.3 | 10 | uM |
| XMD-12 | HeLa | CHK1 | DIkPENLLLDER | Lys2 | 14.9 | 10 | uM |
| XMD-12 | PC-3 | CHK2 | VAIkIISK | Lys1 | 22.9 | 10 | uM |
| XMD-12 | PC-3 | CHK2 | DLkPENVLLSSQEEDCLIK | Lys2 | 29.7 | 10 | uM |
| XMD-12 | HeLa | CHK2 | DLkPENVLLSSQEEDCLIK | Lys2 | 17.6 | 10 | uM |
| XMD-12 | PC-3 | CK1d,CK1e | DVkPDNFLMGLGKK | Lys2 | 11.8 | 10 | uM |
| XMD-12 | PC-3 | CK2a2 | DVkPHNVMIDHQQK | Lys2 | 33.4 | 10 | uM |
| XMD-12 | PC-3 | CLK2 | LTHTDLkPENILFVNSDYELTYNLEK | Lys2 | 5.8 | 10 | uM |
| XMD-12 | HeLa | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | -14.1 | 10 | uM |
| XMD-12 | PC-3 | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | -23.4 | 10 | uM |
| XMD-12 | HeLa | DGKA | IDPVPNTHPLLVFVNPkSGGK | ATP | 5.9 | 10 | uM |
| XMD-12 | HeLa | DMPK | DIkPDNILLDR | Lys2 | -4.3 | 10 | uM |
| XMD-12 | PC-3 | DNAPK | GHDEREHPFLVkGGEDLRQDQR | ATP | 51.4 | 10 | uM |
| XMD-12 | HeLa | DNAPK | GHDEREHPFLVkGGEDLRQDQR | ATP | 30.5 | 10 | uM |
| XMD-12 | PC-3 | DNAPK | kGGSWIQEINVAEK | ATP | 75.9 | 10 | uM |
| XMD-12 | PC-3 | eEF2K | YIkYNSNSGFVR | Protein Kinase Domain | -2.6 | 10 | uM |
| XMD-12 | HeLa | eEF2K | YIkYNSNSGFVR | Protein Kinase Domain | -9.2 | 10 | uM |
| XMD-12 | PC-3 | EGFR | ITDFGLAkLLGAEEK | Activation Loop | -24.0 | 10 | uM |
| XMD-12 | PC-3 | EGFR | LLGAEEKEYHAEGGkVPIK | Activation Loop | -26.4 | 10 | uM |