XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| XMD-12 | PC-3 | MK03 | DLkPSNLLINTTCDLK | Lys2 | -24.1 | 10 | uM |
| XMD-12 | PC-3 | FYN,SRC,YES | QGAkFPIKWTAPEAALYGR | Activation Loop | 70.5 | 10 | uM |
| XMD-12 | PC-3 | eEF2K | YIkYNSNSGFVR | Protein Kinase Domain | -2.6 | 10 | uM |
| XMD-12 | PC-3 | EPHA2 | VLEDDPEATYTTSGGkIPIR | Activation Loop | 2.2 | 10 | uM |
| XMD-12 | PC-3 | FER | TSVAVkTCKEDLPQELK | Lys1 | 42.4 | 10 | uM |
| XMD-12 | PC-3 | AMPKa1,AMPKa2 | VAVkILNR | Lys1 | 90.3 | 10 | uM |
| XMD-12 | PC-3 | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | -23.4 | 10 | uM |
| XMD-12 | PC-3 | DNAPK | GHDEREHPFLVkGGEDLRQDQR | ATP | 51.4 | 10 | uM |
| XMD-12 | PC-3 | EGFR | IPVAIkELR | Lys1 | -0.3 | 10 | uM |
| XMD-12 | PC-3 | AMPKa1,AMPKa2 | DLkPENVLLDAHMNAK | Lys2 | 91.5 | 10 | uM |
| XMD-12 | PC-3 | AGK | ATVFLNPAACkGK | ATP | -6.7 | 10 | uM |
| XMD-12 | PC-3 | FAK | CIGEGQFGDVHQGIYMSPENPALAVAIkTCK | Lys1 | 85.4 | 10 | uM |
| XMD-12 | PC-3 | CaMK2g | TSTQEYAAkIINTK | Lys1 | 33.0 | 10 | uM |
| XMD-12 | PC-3 | CASK | ETGQQFAVkIVDVAK | Lys1 | 22.4 | 10 | uM |
| XMD-12 | PC-3 | CDK10 | DLkVSNLLMTDK | Lys2 | 81.3 | 10 | uM |
| XMD-12 | PC-3 | CDK11,CDK8 | DLkPANILVMGEGPER | Lys2 | 7.1 | 10 | uM |
| XMD-12 | PC-3 | DNAPK | kGGSWIQEINVAEK | ATP | 75.9 | 10 | uM |
| XMD-12 | PC-3 | CDK2 | DLkPQNLLINTEGAIK | Lys2 | -4.2 | 10 | uM |
| XMD-12 | PC-3 | CDK5 | NRETHEIVALkR | Lys1 | 2.4 | 10 | uM |
| XMD-12 | PC-3 | ATR | FYIMMCkPK | ATP | 16.8 | 10 | uM |
| XMD-12 | PC-3 | CDK9 | DMkAANVLITR | Lys2 | 14.3 | 10 | uM |
| XMD-12 | PC-3 | CHK2 | VAIkIISK | Lys1 | 22.9 | 10 | uM |
| XMD-12 | PC-3 | KC1A | DIkPDNFLMGIGR | Lys2 | 28.1 | 10 | uM |
| XMD-12 | PC-3 | CK1d,CK1e | DVkPDNFLMGLGKK | Lys2 | 11.8 | 10 | uM |
| XMD-12 | PC-3 | GCN2_domain2 | DLkPVNIFLDSDDHVK | Lys2 | 0.2 | 10 | uM |