XMD-12 KiNativ -- single dose experiment - Dataset - HMS LINCS Database

XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)

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Small molecules	Cells	Proteins

Small Molecule	Cell Line	Protein	Sequence	Labeling Site	% Inhibition	Assay compound conc	Conc unit
XMD-12	HeLa	RIPK3	DLkPSNVLLDPELHVK	Lys2	1.9	10	uM
XMD-12	PC-3	ROCK1	kLQLELNQER	Other	-25.8	10	uM
XMD-12	PC-3	ROCK1,ROCK2	DVkPDNMLLDK	Lys2	6.0	10	uM
XMD-12	PC-3	RON	IQCAIkSLSR	Lys1	15.8	10	uM
XMD-12	HeLa	RSK1 domain1	LTDFGLSkEAIDHEK	Activation Loop	27.4	10	uM
XMD-12	HeLa	RSK1,RSK2_domain1	DLkPENILLDEEGHIKLTDFGLSK	Lys2	28.2	10	uM
XMD-12	HeLa	RSK1,RSK4 domain1	VLGQGSFGkVFLVR	ATP Loop	-11.2	10	uM
XMD-12	HeLa	RSK2_domain1	LTDFGLSkESIDHEKK	Activation Loop	61.2	10	uM
XMD-12	HeLa	RSK2_domain2	SkRDPTEEIEILLR	Protein Kinase Domain	14.8	10	uM
XMD-12	PC-3	RSK2_domain2	DLkPSNILYVDESGNPESIR	Lys2	34.1	10	uM
XMD-12	PC-3	RSK2_domain2	SkRDPTEEIEILLR	Protein Kinase Domain	49.7	10	uM
XMD-12	HeLa	RSKL1_domain1	VLGVIDkVLLVMDTR	Protein Kinase Domain	-23.2	10	uM
XMD-12	HeLa	SGK3	FYAVkVLQK	Lys1	-8.8	10	uM
XMD-12	HeLa	SLK	DLkAGNILFTLDGDIK	Lys2	6.8	10	uM
XMD-12	PC-3	SLK	ETSVLAAAkVIDTK	Lys1	34.1	10	uM
XMD-12	PC-3	SLK	DLkAGNILFTLDGDIK	Lys2	-4.1	10	uM
XMD-12	HeLa	SMG1	DTVTIHSVGGTITILPTkTKPK	ATP	-5.5	10	uM
XMD-12	PC-3	SNRK	DLkPENVVFFEK	Lys2	-15.0	10	uM
XMD-12	PC-3	SRC	VAIkTLKPGTMSPEAFLQEAQVMK	Lys1	94.6	10	uM
XMD-12	PC-3	SRPK1	IIHTDIkPENILLSVNEQYIR	Lys2	22.2	10	uM
XMD-12	PC-3	SRPK1/2	FVAMkVVK	Lys1	44.7	10	uM
XMD-12	HeLa	STLK5	YSVkVLPWLSPEVLQQNLQGYDAK	Activation Loop		10	uM
XMD-12	HeLa	SYK	ISDFGLSkALR	Activation Loop	2.1	10	uM
XMD-12	HeLa	TAO1,TAOK3	DIkAGNILLTEPGQVK	Lys2	28.9	10	uM
XMD-12	PC-3	TAO1,TAOK3	DIkAGNILLTEPGQVK	Lys2	52.3	10	uM