XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
XMD-12 PC-3 TAOK2
DVkAGNILLSEPGLVK
Lys2
91.3
 10
uM
XMD-12 HeLa TBK1
TGDLFAIkVFNNISFLRPVDVQMR
Lys1
 10
uM
XMD-12 HeLa TEC
YVLDDQYTSSSGAkFPVK
Activation Loop
11.2
 10
uM
XMD-12 HeLa TLK1
YAAVkIHQLNK
Lys1
-23.8
 10
uM
XMD-12 PC-3 TLK1
YLNEIKPPIIHYDLkPGNILLVDGTACGEIK
Lys2
-7.5
 10
uM
XMD-12 HeLa TLK1
YLNEIKPPIIHYDLkPGNILLVDGTACGEIK
Lys2
-20.1
 10
uM
XMD-12 PC-3 TLK1
YAAVkIHQLNK
Lys1
-47.5
 10
uM
XMD-12 PC-3 TLK2
YVAVkIHQLNK
Lys1
-11.7
 10
uM
XMD-12 HeLa ULK1
DLkPQNILLSNPAGR
Lys2
-9.3
 10
uM
XMD-12 HeLa ULK3
EVVAIkCVAK
Lys1
34.2
 10
uM
XMD-12 HeLa WEE1
YIHSMSLVHMDIkPSNIFISR
Lys2
 10
uM
XMD-12 HeLa Wnk1,Wnk2,Wnk3
DLkCDNIFITGPTGSVK
Lys2
2.8
 10
uM
XMD-12 PC-3 Wnk1,Wnk2,Wnk4
IGDLGLATLkR
Activation Loop
-11.9
 10
uM
XMD-12 PC-3 WNK4
DLkCDNVFITGPTGSVK
Lys2
-10.1
 10
uM
XMD-12 PC-3 ZC1/HGK,ZC2/TNIK,ZC3/MINK
DIkGQNVLLTENAEVK
Lys2
-7.1
 10
uM
XMD-12 HeLa ZC1/HGK,ZC2/TNIK,ZC3/MINK
DIkGQNVLLTENAEVK
Lys2
22.4
 10
uM