XMD-12 KiNativ -- single dose experiment - Dataset - HMS LINCS Database

XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)

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Small molecules	Cells	Proteins

Small Molecule	Cell Line	Protein	Sequence	Labeling Site	% Inhibition	Assay compound conc	Conc unit
XMD-12	PC-3	SLK	DLkAGNILFTLDGDIK	Lys2	-4.1	10	uM
XMD-12	PC-3	SLK	ETSVLAAAkVIDTK	Lys1	34.1	10	uM
XMD-12	HeLa	SLK	DLkAGNILFTLDGDIK	Lys2	6.8	10	uM
XMD-12	HeLa	SGK3	FYAVkVLQK	Lys1	-8.8	10	uM
XMD-12	HeLa	RSKL1_domain1	VLGVIDkVLLVMDTR	Protein Kinase Domain	-23.2	10	uM
XMD-12	PC-3	RSK2_domain2	SkRDPTEEIEILLR	Protein Kinase Domain	49.7	10	uM
XMD-12	HeLa	RSK2_domain2	SkRDPTEEIEILLR	Protein Kinase Domain	14.8	10	uM
XMD-12	PC-3	RSK2_domain2	DLkPSNILYVDESGNPESIR	Lys2	34.1	10	uM
XMD-12	HeLa	RSK2_domain1	LTDFGLSkESIDHEKK	Activation Loop	61.2	10	uM
XMD-12	HeLa	RSK1,RSK4 domain1	VLGQGSFGkVFLVR	ATP Loop	-11.2	10	uM
XMD-12	HeLa	RSK1,RSK2_domain1	DLkPENILLDEEGHIKLTDFGLSK	Lys2	28.2	10	uM
XMD-12	HeLa	RSK1 domain1	LTDFGLSkEAIDHEK	Activation Loop	27.4	10	uM
XMD-12	PC-3	RON	IQCAIkSLSR	Lys1	15.8	10	uM
XMD-12	PC-3	ROCK1,ROCK2	DVkPDNMLLDK	Lys2	6.0	10	uM
XMD-12	PC-3	ROCK1	kLQLELNQER	Other	-25.8	10	uM
XMD-12	HeLa	RIPK3	DLkPSNVLLDPELHVK	Lys2	1.9	10	uM
XMD-12	PC-3	PRPK	FLSGLELVkQGAEAR	ATP Loop	-16.3	10	uM
XMD-12	HeLa	PRPK	FLSGLELVkQGAEAR	ATP Loop	-11.6	10	uM
XMD-12	PC-3	PRP4	CNILHADIkPDNILVNESK	Lys2	-13.9	10	uM
XMD-12	HeLa	PLK1	DLkLGNLFLNEDLEVK	Lys2	10.9	10	uM
XMD-12	HeLa	PKR	DLkPSNIFLVDTK	Lys2	-9.5	10	uM
XMD-12	PC-3	PKR	DLkPSNIFLVDTK	Lys2	-38.5	10	uM
XMD-12	HeLa	PKN1	GHFGkVLLSEFRPSGELFAIK	Lys1	-20.6	10	uM
XMD-12	PC-3	PKD2	DVAVkVIDK	Lys1	33.2	10	uM
XMD-12	HeLa	PKD2	DVAVkVIDK	Lys1	5.0	10	uM