XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
XMD-12 HeLa CaMK1a
LVAIkCIAK
Lys1
-16.8
 10
uM
XMD-12 HeLa BTK
GQYDVAIkMIK
Lys1
28.3
 10
uM
XMD-12 HeLa BRAF
DLkSNNIFLHEDLTVK
Lys2
-6.9
 10
uM
XMD-12 HeLa BARK1
DLkPANILLDEHGHVR
Lys2
-4.3
 10
uM
XMD-12 HeLa AurB
SHFIVALkVLFK
Lys1
95.0
 10
uM
XMD-12 PC-3 ATR
FYIMMCkPK
ATP
16.8
 10
uM
XMD-12 HeLa ATR
FYIMMCkPK
ATP
-2.1
 10
uM
XMD-12 HeLa ARAF
DLkSNNIFLHEGLTVK
Lys2
1.1
 10
uM
XMD-12 PC-3 ANPb
GMAFLHNSIISSHGSLkSSNCVVDSR
Lys2
-7.0
 10
uM
XMD-12 PC-3 AMPKa1,AMPKa2
DLkPENVLLDAHMNAK
Lys2
91.5
 10
uM
XMD-12 HeLa AMPKa1,AMPKa2
VAVkILNR
Lys1
88.7
 10
uM
XMD-12 HeLa AMPKa1,AMPKa2
DLkPENVLLDAHMNAK
Lys2
88.8
 10
uM
XMD-12 PC-3 AMPKa1,AMPKa2
VAVkILNR
Lys1
90.3
 10
uM
XMD-12 PC-3 AGK
ATVFLNPAACkGK
ATP
-6.7
 10
uM
XMD-12 HeLa ACK
TVSVAVkCLKPDVLSQPEAMDDFIR
Lys1
87.9
 10
uM
XMD-12 HeLa ABL,ARG
LMTGDTYTAHAGAkFPIK
Activation Loop
70.4
 10
uM