JWE-035 KiNativ -- single dose experiment - Dataset (ID:20100)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
JWE-035 PC-3 TAOK2
DVkAGNILLSEPGLVK
Lys2
71.7
 10
uM
JWE-035 HeLa TBK1
TGDLFAIkVFNNISFLRPVDVQMR
Lys1
28.7
 10
uM
JWE-035 HeLa TEC
YVLDDQYTSSSGAkFPVK
Activation Loop
12.1
 10
uM
JWE-035 HeLa TLK1
YLNEIKPPIIHYDLkPGNILLVDGTACGEIK
Lys2
-10.4
 10
uM
JWE-035 PC-3 TLK1
YLNEIKPPIIHYDLkPGNILLVDGTACGEIK
Lys2
-1.1
 10
uM
JWE-035 HeLa TLK1
YAAVkIHQLNK
Lys1
-48.4
 10
uM
JWE-035 PC-3 TLK1
YAAVkIHQLNK
Lys1
37.8
 10
uM
JWE-035 PC-3 TLK2
YVAVkIHQLNK
Lys1
12.7
 10
uM
JWE-035 HeLa ULK1
DLkPQNILLSNPAGR
Lys2
22.8
 10
uM
JWE-035 HeLa ULK3
EVVAIkCVAK
Lys1
8.2
 10
uM
JWE-035 HeLa WEE1
YIHSMSLVHMDIkPSNIFISR
Lys2
14.5
 10
uM
JWE-035 HeLa Wnk1,Wnk2,Wnk3
DLkCDNIFITGPTGSVK
Lys2
10.7
 10
uM
JWE-035 PC-3 Wnk1,Wnk2,Wnk4
IGDLGLATLkR
Activation Loop
-0.3
 10
uM
JWE-035 PC-3 WNK4
DLkCDNVFITGPTGSVK
Lys2
-13.1
 10
uM
JWE-035 HeLa ZC1/HGK,ZC2/TNIK,ZC3/MINK
DIkGQNVLLTENAEVK
Lys2
3.8
 10
uM
JWE-035 PC-3 ZC1/HGK,ZC2/TNIK,ZC3/MINK
DIkGQNVLLTENAEVK
Lys2
3.1
 10
uM