JWE-035 KiNativ -- single dose experiment - Dataset (ID:20100)

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Small Molecule Cell Line Protein Sequence Labeling Site % Inhibition Assay compound conc Conc unit
JWE-035 PC-3 EphA7
VIEDDPEAVYTTTGGkIPVR
Activation Loop
12.3
 10
uM
JWE-035 PC-3 PIK3CB
VFGEDSVGVIFkNGDDLRQDMLTLQMLR
ATP
54.1
 10
uM
JWE-035 HeLa LATS2
VDTHALYAMkTLR
Lys1
11.5
 10
uM
JWE-035 HeLa LYN
VAVkTLKPGTMSVQAFLEEANLMK
Lys1
25.7
 10
uM
JWE-035 PC-3 AMPKa1,AMPKa2
VAVkILNR
Lys1
75.7
 10
uM
JWE-035 HeLa AMPKa1,AMPKa2
VAVkILNR
Lys1
55.4
 10
uM
JWE-035 PC-3 SRC
VAIkTLKPGTMSPEAFLQEAQVMK
Lys1
-2.0
 10
uM
JWE-035 PC-3 CHK2
VAIkIISK
Lys1
42.7
 10
uM
JWE-035 HeLa ACK
TVSVAVkCLKPDVLSQPEAMDDFIR
Lys1
30.9
 10
uM
JWE-035 PC-3 FER
TSVAVkTCKEDLPQELK
Lys1
-8.1
 10
uM
JWE-035 HeLa FER
TSVAVkTCKEDLPQELK
Lys1
14.6
 10
uM
JWE-035 PC-3 CaMK2g
TSTQEYAAkIINTK
Lys1
21.0
 10
uM
JWE-035 HeLa CaMK2g
TSTQEYAAkIINTK
Lys1
19.9
 10
uM
JWE-035 PC-3 PI42C
TLVIkEVSSEDIADMHSNLSNYHQYIVK
ATP
76.9
 10
uM
JWE-035 HeLa PI42C
TLVIkEVSSEDIADMHSNLSNYHQYIVK
ATP
83.0
 10
uM
JWE-035 HeLa TBK1
TGDLFAIkVFNNISFLRPVDVQMR
Lys1
28.7
 10
uM
JWE-035 HeLa PIK3C3
TEDGGKYPVIFkHGDDLR
ATP
27.9
 10
uM
JWE-035 HeLa RSK2_domain2
SkRDPTEEIEILLR
Protein Kinase Domain
16.9
 10
uM
JWE-035 PC-3 RSK2_domain2
SkRDPTEEIEILLR
Protein Kinase Domain
26.4
 10
uM
JWE-035 HeLa KSR1,KSR2
SkNVFYDNGK
Protein Kinase Domain
-48.5
 10
uM
JWE-035 HeLa IRAK3
SHLEHQSCTINMTSSSSkHLWYMPEEYIR
Protein Kinase Domain
33.0
 10
uM
JWE-035 HeLa AurB
SHFIVALkVLFK
Lys1
80.4
 10
uM
JWE-035 HeLa PI4KA,PI4KAP2
SGTPMQSAAkAPYLAK
ATP
30.8
 10
uM
JWE-035 PC-3 PI4KA,PI4KAP2
SGTPMQSAAkAPYLAK
ATP
6.8
 10
uM
JWE-035 HeLa IKKE
SGELVAVkVFNTTSYLRPR
Lys1
0.0
 10
uM