XMD16-144 KiNativ -- single dose experiment - Dataset (ID:20099)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| XMD16-144 | PC-3 | CDK2 | DLkPQNLLINTEGAIK | Lys2 | 5.9 | 10 | uM |
| XMD16-144 | HeLa | CDK2 | DLkPQNLLINTEGAIK | Lys2 | -11.0 | 10 | uM |
| XMD16-144 | PC-3 | CDK5 | DLkPQNLLINR | Lys2 | -7.3 | 10 | uM |
| XMD16-144 | PC-3 | CDK5 | NRETHEIVALkR | Lys1 | -1.9 | 10 | uM |
| XMD16-144 | PC-3 | CDK5 | ETHEIVALkR | Lys1 | -2.8 | 10 | uM |
| XMD16-144 | HeLa | CDK7 | DLkPNNLLLDENGVLK | Lys2 | 45.8 | 10 | uM |
| XMD16-144 | PC-3 | CDK9 | DMkAANVLITR | Lys2 | -34.5 | 10 | uM |
| XMD16-144 | HeLa | CHK1 | DIkPENLLLDER | Lys2 | 27.5 | 10 | uM |
| XMD16-144 | PC-3 | CHK2 | VAIkIISK | Lys1 | 49.6 | 10 | uM |
| XMD16-144 | PC-3 | CHK2 | DLkPENVLLSSQEEDCLIK | Lys2 | 37.1 | 10 | uM |
| XMD16-144 | HeLa | CHK2 | DLkPENVLLSSQEEDCLIK | Lys2 | 19.0 | 10 | uM |
| XMD16-144 | PC-3 | CK1d,CK1e | DVkPDNFLMGLGKK | Lys2 | -12.3 | 10 | uM |
| XMD16-144 | PC-3 | CK2a2 | DVkPHNVMIDHQQK | Lys2 | 20.2 | 10 | uM |
| XMD16-144 | PC-3 | CLK2 | LTHTDLkPENILFVNSDYELTYNLEK | Lys2 | 10.0 | 10 | uM |
| XMD16-144 | HeLa | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | -2.0 | 10 | uM |
| XMD16-144 | PC-3 | CSK | VSDFGLTkEASSTQDTGKLPVK | Activation Loop | 13.9 | 10 | uM |
| XMD16-144 | HeLa | DGKA | IDPVPNTHPLLVFVNPkSGGK | ATP | -1.7 | 10 | uM |
| XMD16-144 | HeLa | DMPK | DIkPDNILLDR | Lys2 | -6.6 | 10 | uM |
| XMD16-144 | PC-3 | DNAPK | GHDEREHPFLVkGGEDLRQDQR | ATP | 73.5 | 10 | uM |
| XMD16-144 | HeLa | DNAPK | GHDEREHPFLVkGGEDLRQDQR | ATP | 46.1 | 10 | uM |
| XMD16-144 | PC-3 | DNAPK | kGGSWIQEINVAEK | ATP | 82.5 | 10 | uM |
| XMD16-144 | PC-3 | eEF2K | YIkYNSNSGFVR | Protein Kinase Domain | -3.6 | 10 | uM |
| XMD16-144 | HeLa | eEF2K | YIkYNSNSGFVR | Protein Kinase Domain | 0.2 | 10 | uM |
| XMD16-144 | PC-3 | EGFR | ITDFGLAkLLGAEEK | Activation Loop | -7.5 | 10 | uM |
| XMD16-144 | PC-3 | EGFR | LLGAEEKEYHAEGGkVPIK | Activation Loop | -2.5 | 10 | uM |