Torin2 KiNativ -- single dose experiment - Dataset - HMS LINCS Database

Torin2 KiNativ -- single dose experiment - Dataset (ID:20095)

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Small molecules	Cells	Proteins

Small Molecule	Cell Line	Protein	Sequence	Labeling Site	% Inhibition	Assay compound conc	Conc unit
Torin2	HeLa	EPHA2	VLEDDPEATYTTSGGkIPIR	Activation Loop	22.2	10	uM
Torin2	HeLa	CSK	VSDFGLTkEASSTQDTGKLPVK	Activation Loop	-1.4	10	uM
Torin2	HeLa	Wnk1,Wnk2,Wnk4	IGDLGLATLkR	Activation Loop	-23.1	10	uM
Torin2	HeLa	MAP2K3	MCDFGISGYLVDSVAkTMDAGCKPYMAPER	Activation Loop	8.4	10	uM
Torin2	HeLa	JAK1_domain2	IGDFGLTkAIETDKEYYTVK	Activation Loop	40.0	10	uM
Torin2	HeLa	EPHB4	FLEENSSDPTYTSSLGGkIPIR	Activation Loop	-6.8	10	uM
Torin2	HeLa	RSK1_domain1	LTDFGLSkEAIDHEKK	Activation Loop	2.9	10	uM
Torin2	HeLa	RSK2_domain1	LTDFGLSkESIDHEKK	Activation Loop	7.1	10	uM
Torin2	HeLa	EGFR	LLGAEEKEYHAEGGkVPIK	Activation Loop	17.9	10	uM
Torin2	HeLa	JAK1 domain2	IGDFGLTkAIETDKEYYTVKDDR	Activation Loop	52.3	10	uM
Torin2	HeLa	MAP2K6	MCDFGISGYLVDSVAkTIDAGCKPYMAPER	Activation Loop	20.5	10	uM
Torin2	HeLa	MST3,MST4,YSK1	LADFGVAGQLTDTQIkR	Activation Loop	-1.0	10	uM
Torin2	HeLa	NDR1,NDR2	LSDFGLCTGLkK	Activation Loop	9.9	10	uM
Torin2	HeLa	PKR	IGDFGLVTSLkNDGKR	Activation Loop	7.7	10	uM
Torin2	HeLa	ABL,ARG	LMTGDTYTAHAGAkFPIK	Activation Loop	2.7	10	uM
Torin2	HeLa	FYN,SRC,YES	QGAkFPIKWTAPEAALYGR	Activation Loop	53.1	10	uM
Torin2	HeLa	FER	QEDGGVYSSSGLkQIPIKWTAPEALNYGR	Activation Loop	6.5	10	uM
Torin2	HeLa	PI4KA,PI4KAP2	SGTPMQSAAkAPYLAK	ATP	30.4	10	uM
Torin2	HeLa	PIK3C3	TEDGGkYPVIFKHGDDLR	ATP	>85	10	uM
Torin2	HeLa	PIK3CB	VFGEDSVGVIFkNGDDLRQDMLTLQMLR	ATP	80.3	10	uM
Torin2	HeLa	PI42C	TLVIkEVSSEDIADMHSNLSNYHQYIVK	ATP	54.7	10	uM
Torin2	HeLa	FYV1	GGkSGAAFYATEDDRFILK	ATP	50.8	10	uM
Torin2	HeLa	DNAPK	EHPFLVkGGEDLR	ATP	99.5	10	uM
Torin2	HeLa	DNAPK	GHDEREHPFLVkGGEDLR	ATP	99.5	10	uM
Torin2	HeLa	AGK	ATVFLNPAACkGK	ATP	20.1	10	uM