Sulindac sulfide - Small Molecule (ID:10518-101)
| HMS LINCS ID: |
10518-101
|
| Name: | Sulindac sulfide |
| Alternative Names: | |
| LINCS ID: | |
| PubChem CID: | 5352624 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 340.09 |
| InChi: | InChI=1S/C20H17FO2S/c1-12-17(9-13-3-6-15(24-2)7-4-13)16-8-5-14(21)10-19(16)18(12)11-20(22)23/h3-10H,11H2,1-2H3,(H,22,23)/b17-9- |
| InChi Key: | LFWHFZJPXXOYNR-MFOYZWKCSA-N |
| SMILES: | CC\1=C(C2=C(/C1=C\C3=CC=C(C=C3)SC)C=CC(=C2)F)CC(=O)O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-05-06 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
Akr1b1, COX1, PTGS1 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | MT-CO1, MT-CO2, PTGS1, PTGS2 |
3 (equivalent to 1µM ≤ Kd < 10 µM) | MAPK1 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20268 | Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. | Analysis |
| 20269 | Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 2 of 4: Calculated dose-response metrics. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10518-101-1 | Sigma-Aldrich |
(Kd <100 nM)