Vincristine - Small Molecule (ID:10488-114)
| HMS LINCS ID: |
10488-114
|
| Name: | Vincristine |
| Alternative Names: | Leurocristine; 22-Oxovincaleukoblastine; Oncovine; Vincrystine; Vinkristin |
| LINCS ID: | |
| PubChem CID: | 5978 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 824.40 |
| InChi: | InChI=1S/C46H56N4O10/c1-7-42(55)22-28-23-45(40(53)58-5,36-30(14-18-48(24-28)25-42)29-12-9-10-13-33(29)47-36)32-20-31-34(21-35(32)57-4)50(26-51)38-44(31)16-19-49-17-11-15-43(8-2,37(44)49)39(60-27(3)52)46(38,56)41(54)59-6/h9-13,15,20-21,26,28,37-39,47,55-56H,7-8,14,16-19,22-25H2,1-6H3/t28-,37+,38-,39-,42+,43-,44-,45+,46+/m1/s1 |
| InChi Key: | OGWKCGZFUXNPDA-XQKSVPLYSA-N |
| SMILES: | CC[C@@]1(C[C@@H]2C[C@@](C3=C(CCN(C2)C1)C4=CC=CC=C4N3)(C5=C(C=C6C(=C5)[C@]78CCN9[C@H]7[C@@](C=CC9)([C@H]([C@@]([C@@H]8N6C=O)(C(=O)OC)O)OC(=O)C)CC)OC)C(=O)OC)O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
TUBB | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | TUBB2B |
Batch Information for HMSL10488-114-1:
| HMS LINCS Batch ID: | 10488-114-1 |
| Provider: | Sigma-Aldrich |
| Provider Batch ID: | |
| Salt: | 114 |
| Molecular Formula: | C46H58N4O14S |
| Molecular Weight: | 923.04 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-12-10 |
| Most Recent Update: | 2016-12-02 |
(equivalent to 100 nM ≤ Kd < 1µM)