Mitoxantrone - Small Molecule (ID:10479-102)
| HMS LINCS ID: |
10479-102
|
| Name: | Mitoxantrone |
| Alternative Names: | CL 232325; CL-232325; DHAQ; Novantron; Novantrone |
| LINCS ID: | LSM-2481 |
| PubChem CID: | 4212 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 444.20 |
| InChi: | InChI=1S/C22H28N4O6/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32/h1-4,23-30H,5-12H2 |
| InChi Key: | KKZJGLLVHKMTCM-UHFFFAOYSA-N |
| SMILES: | C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
SLC47A1, TOP2A, TOP2B | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | ALOX15, BTK, Dyrk1a, MBNL1, WHSC1 |
10 (confirmed non-binding) |
Batch Information for HMSL10479-102-1:
| HMS LINCS Batch ID: | 10479-102-1 |
| Provider: | Sigma-Aldrich |
| Provider Batch ID: | 050M1241 |
| Salt: | 102 |
| Molecular Formula: | C22H30Cl2N4O6 |
| Molecular Weight: | 517.4 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-08-24 |
| Most Recent Update: | 2016-04-04 |
(equivalent to 100 nM ≤ Kd < 1µM)