EW-7197 - Small Molecule (ID:10447-101)
| HMS LINCS ID: |
10447-101
|
| Name: | EW-7197 |
| Alternative Names: | |
| LINCS ID: | |
| PubChem CID: | 54766013 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 399.16 |
| InChi: | InChI=1S/C22H18FN7/c1-14-5-4-8-18(27-14)22-21(15-9-10-20-25-13-26-30(20)12-15)28-19(29-22)11-24-17-7-3-2-6-16(17)23/h2-10,12-13,24H,11H2,1H3,(H,28,29) |
| InChi Key: | FJCDSQATIJKQKA-UHFFFAOYSA-N |
| SMILES: | CC1=CC=CC(=N1)C2=C(N=C(N2)CNC3=CC=CC=C3F)C4=CN5C(=NC=N5)C=C4 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
ACVR1B, KDR, RIPK2, Tgfbr1, TGFBR1 | |
3 (equivalent to 1µM ≤ Kd < 10 µM) | MAPK14 |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10447-101-1 | Selleck Chemicals | S753001 |
(Kd <100 nM)