VX-702 - Small Molecule (ID:10440-101)

HMS LINCS ID: 10440-101
Name: VX-702
Alternative Names:
LINCS ID:
PubChem CID: 10341154
ChEBI ID:
ChEMBL ID:
Molecular Mass: 404.09
InChi: InChI=1S/C19H12F4N4O2/c20-9-4-5-10(14(23)8-9)16-11(18(24)28)6-7-15(26-16)27(19(25)29)17-12(21)2-1-3-13(17)22/h1-8H,(H2,24,28)(H2,25,29)
InChi Key: FYSRKRZDBHOFAY-UHFFFAOYSA-N
SMILES: C1=CC(=C(C(=C1)F)N(C2=NC(=C(C=C2)C(=O)N)C3=C(C=C(C=C3)F)F)C(=O)N)F
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
ACVR2B, MAPK11, MAPK14
2
(equivalent to 100 nM ≤ Kd < 1µM)
MAPK10, NLK
3
(equivalent to 1µM ≤ Kd < 10 µM)
MAPK9, PI4KB, PKD2, PRKD2, PRKD3, ROCK1

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10440-101-1 MedChem Express 04908