VX-702 - Small Molecule (ID:10440-101)
| HMS LINCS ID: |
10440-101
|
| Name: | VX-702 |
| Alternative Names: | |
| LINCS ID: | |
| PubChem CID: | 10341154 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 404.09 |
| InChi: | InChI=1S/C19H12F4N4O2/c20-9-4-5-10(14(23)8-9)16-11(18(24)28)6-7-15(26-16)27(19(25)29)17-12(21)2-1-3-13(17)22/h1-8H,(H2,24,28)(H2,25,29) |
| InChi Key: | FYSRKRZDBHOFAY-UHFFFAOYSA-N |
| SMILES: | C1=CC(=C(C(=C1)F)N(C2=NC(=C(C=C2)C(=O)N)C3=C(C=C(C=C3)F)F)C(=O)N)F |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
ACVR2B, MAPK11, MAPK14 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | MAPK10, NLK |
3 (equivalent to 1µM ≤ Kd < 10 µM) | MAPK9, PI4KB, PKD2, PRKD2, PRKD3, ROCK1 |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10440-101-1 | MedChem Express | 04908 |
(Kd <100 nM)