VX-702 - Small Molecule (ID:10440-101)
| HMS LINCS ID: |
10440-101
|
| Name: | VX-702 |
| Alternative Names: | |
| LINCS ID: | |
| PubChem CID: | 10341154 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 404.09 |
| InChi: | InChI=1S/C19H12F4N4O2/c20-9-4-5-10(14(23)8-9)16-11(18(24)28)6-7-15(26-16)27(19(25)29)17-12(21)2-1-3-13(17)22/h1-8H,(H2,24,28)(H2,25,29) |
| InChi Key: | FYSRKRZDBHOFAY-UHFFFAOYSA-N |
| SMILES: | C1=CC(=C(C(=C1)F)N(C2=NC(=C(C=C2)C(=O)N)C3=C(C=C(C=C3)F)F)C(=O)N)F |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
ACVR2B, MAPK11, MAPK14 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | MAPK10, NLK |
3 (equivalent to 1µM ≤ Kd < 10 µM) | MAPK9, PI4KB, PKD2, PRKD2, PRKD3, ROCK1 |
Batch Information for HMSL10440-101-1:
| HMS LINCS Batch ID: | 10440-101-1 |
| Provider: | MedChem Express |
| Provider Batch ID: | 04908 |
| Salt: | 101 |
| Molecular Formula: | C19H12F4N4O2 |
| Molecular Weight: | 404.32 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-08-27 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10440-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 08/31/2015 | PASS | HMSL10440-101-1_LCMS.pdf |
(Kd <100 nM)