AZD2014 - Small Molecule (ID:10437-101)
| HMS LINCS ID: |
10437-101
|
| Name: | AZD2014 |
| Alternative Names: | |
| LINCS ID: | |
| PubChem CID: | 25262792 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 462.24 |
| InChi: | InChI=1S/C25H30N6O3/c1-16-14-33-11-9-30(16)23-20-7-8-21(18-5-4-6-19(13-18)24(32)26-3)27-22(20)28-25(29-23)31-10-12-34-15-17(31)2/h4-8,13,16-17H,9-12,14-15H2,1-3H3,(H,26,32)/t16-,17-/m0/s1 |
| InChi Key: | JUSFANSTBFGBAF-IRXDYDNUSA-N |
| SMILES: | C[C@H]1COCCN1C2=NC(N3CCOC[C@@H]3C)=NC4=C2C=CC(C5=CC(C(NC)=O)=CC=C5)=N4 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
FKBP1A, MTOR | |
10 (confirmed non-binding) |
Datasets:
| HMS Dataset ID | Dataset Title | HMS Dataset Type |
|---|---|---|
| 20000 | Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library. | Analysis |
| 20354 | Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 1 of 2: Normalized growth rate inhibition values | Microscopy/Imaging |
| 20355 | Breast Cancer Profiling Project, Drug Sensitivity phase II: Fixed-cell GR measures of 33 breast cell lines and PDX lines to 16 small molecule perturbagens from library plate II. Dataset 2 of 2: Calculated dose response metrics | Analysis |
Batch Information:
| HMS LINCS Batch ID | Provider | Provider Batch ID |
|---|---|---|
| 10437-101-1 | MedChem Express | 08011 |
(equivalent to 100 nM ≤ Kd < 1µM)