BIX 02565 - Small Molecule (ID:10434-101)

HMS LINCS ID: 10434-101
Name: BIX 02565
Alternative Names:
LINCS ID:
PubChem CID: 53246941
ChEBI ID:
ChEMBL ID:
Molecular Mass: 458.24
InChi: InChI=1S/C26H30N6O2/c1-17-11-12-27-25(34)23-15-18-9-10-19(16-22(18)32(17)23)24(33)29-26-28-20-7-4-5-8-21(20)31(26)14-6-13-30(2)3/h4-5,7-10,15-17H,6,11-14H2,1-3H3,(H,27,34)(H,28,29,33)/t17-/m1/s1
InChi Key: ZHMXXVNQAFCXKK-QGZVFWFLSA-N
SMILES: C[C@@H]1CCNC(C2=CC3=C(C=C(C(NC4=NC5=CC=CC=C5N4CCCN(C)C)=O)C=C3)N12)=O
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2016-04-04

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
1
(Kd <100 nM)
LRRK2, PKD1, PRKD1, RPS6KA3
2
(equivalent to 100 nM ≤ Kd < 1µM)
CLK1, CLK2, FGFR2, FLT3, PDGFRA, PKD2, PRKD2, PRKD3, RET

Batch Information for HMSL10434-101-1:

HMS LINCS Batch ID: 10434-101-1
Provider: MedChem Express
Provider Batch ID: 11852
Salt: 101
Molecular Formula: C26H30N6O2
Molecular Weight: 458.56
Purity:
Purification Method:
Chemical Synthesis Reference:
Comments:
Date Publicly Available: 2015-08-27
Most Recent Update: 2016-04-04

HMS QC Testing Events for HMSL10434-101-1:

Date HMS QC Outcome Comment Files
08/31/2015 PASS purity is only ~95% HMSL10434-101-1_NMR.pdf,
HMSL10434-101-1_LCMS.pdf