BIX 02565 - Small Molecule (ID:10434-101)
| HMS LINCS ID: |
10434-101
|
| Name: | BIX 02565 |
| Alternative Names: | |
| LINCS ID: | |
| PubChem CID: | 53246941 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 458.24 |
| InChi: | InChI=1S/C26H30N6O2/c1-17-11-12-27-25(34)23-15-18-9-10-19(16-22(18)32(17)23)24(33)29-26-28-20-7-4-5-8-21(20)31(26)14-6-13-30(2)3/h4-5,7-10,15-17H,6,11-14H2,1-3H3,(H,27,34)(H,28,29,33)/t17-/m1/s1 |
| InChi Key: | ZHMXXVNQAFCXKK-QGZVFWFLSA-N |
| SMILES: | C[C@@H]1CCNC(C2=CC3=C(C=C(C(NC4=NC5=CC=CC=C5N4CCCN(C)C)=O)C=C3)N12)=O |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
LRRK2, PKD1, PRKD1, RPS6KA3 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | CLK1, CLK2, FGFR2, FLT3, PDGFRA, PKD2, PRKD2, PRKD3, RET |
Batch Information for HMSL10434-101-1:
| HMS LINCS Batch ID: | 10434-101-1 |
| Provider: | MedChem Express |
| Provider Batch ID: | 11852 |
| Salt: | 101 |
| Molecular Formula: | C26H30N6O2 |
| Molecular Weight: | 458.56 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-08-27 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10434-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 08/31/2015 | PASS | purity is only ~95% | HMSL10434-101-1_NMR.pdf, HMSL10434-101-1_LCMS.pdf |
(Kd <100 nM)