THZ1 - Small Molecule (ID:10429-101)

HMS LINCS ID: 10429-101
Name: THZ1
Alternative Names:
LINCS ID:
PubChem CID: 73602827
ChEBI ID:
ChEMBL ID:
Molecular Mass: 565.20
InChi: InChI=1S/C31H28ClN7O2/c1-39(2)16-6-11-28(40)35-21-14-12-20(13-15-21)30(41)36-22-7-5-8-23(17-22)37-31-34-19-26(32)29(38-31)25-18-33-27-10-4-3-9-24(25)27/h3-15,17-19,33H,16H2,1-2H3,(H,35,40)(H,36,41)(H,34,37,38)
InChi Key: OBJNFLYHUXWUPF-UHFFFAOYSA-N
SMILES: CN(C)CC=CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=CC(=C2)NC3=NC=C(C(=N3)C4=CNC5=CC=CC=C54)Cl
Relevant Citations:
Comments:
Date Publicly Available:
Most Recent Update: 2017-09-29

Target Affinity:

(see Study 20000)
Target Affinity Spectrum Value HUGO Gene Name
2
(equivalent to 100 nM ≤ Kd < 1µM)
CDK7

Datasets:

HMS Dataset ID Dataset Title HMS Dataset Type
20000
Target Affinity Spectrum (TAS) vectors for compounds in the HMS LINCS small molecule library.
Analysis
20334
THZ1 KINOMEscan
 KINOMEscan

Batch Information:

HMS LINCS Batch ID Provider Provider Batch ID
10429-101-2 Nathanael Gray (DFCI) THZ-2-102-01