PIM12 kinase inhibitor V - Small Molecule (ID:10425-101)
| HMS LINCS ID: |
10425-101
|
| Name: | PIM12 kinase inhibitor V |
| Alternative Names: | TCS-PIM-1-4a; SMI-4A |
| LINCS ID: | |
| PubChem CID: | 1361334 |
| ChEBI ID: | |
| ChEMBL ID: | |
| Molecular Mass: | 273.01 |
| InChi: | InChI=1S/C11H6F3NO2S/c12-11(13,14)7-3-1-2-6(4-7)5-8-9(16)15-10(17)18-8/h1-5H,(H,15,16,17) |
| InChi Key: | NGJLOFCOEOHFKQ-UHFFFAOYSA-N |
| SMILES: | C1=CC(=CC(=C1)C(F)(F)F)C=C2C(=O)NC(=O)S2 |
| Relevant Citations: | |
| Comments: | |
| Date Publicly Available: | |
| Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)| Target Affinity Spectrum Value | HUGO Gene Name |
|---|---|
PIM1 | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | PIM2, TTR |
Batch Information for HMSL10425-101-1:
| HMS LINCS Batch ID: | 10425-101-1 |
| Provider: | MedChem Express |
| Provider Batch ID: | 07611 |
| Salt: | 101 |
| Molecular Formula: | C11H6F3NO2S |
| Molecular Weight: | 273.23 |
| Purity: | |
| Purification Method: | |
| Chemical Synthesis Reference: | |
| Comments: | |
| Date Publicly Available: | 2015-08-27 |
| Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10425-101-1:
| Date | HMS QC Outcome | Comment | Files |
|---|---|---|---|
| 08/31/2015 | PASS | HMSL10425-101-1_NMR.pdf, HMSL10425-101-1_LCMS.pdf |
(Kd <100 nM)