Leflunomide - Small Molecule (ID:10414-101)
HMS LINCS ID: | 10414-101 |
Name: | Leflunomide |
Alternative Names: | HWA486; RS-34821; SU101 |
LINCS ID: | |
PubChem CID: | 3899 |
ChEBI ID: | |
ChEMBL ID: | |
Molecular Mass: | 270.06 |
InChi: | InChI=1S/C12H9F3N2O2/c1-7-10(6-16-19-7)11(18)17-9-4-2-8(3-5-9)12(13,14)15/h2-6H,1H3,(H,17,18) |
InChi Key: | VHOGYURTWQBHIL-UHFFFAOYSA-N |
SMILES: | CC1=C(C=NO1)C(=O)NC2=CC=C(C=C2)C(F)(F)F |
Relevant Citations: | |
Comments: | |
Date Publicly Available: | |
Most Recent Update: | 2016-04-04 |
Target Affinity:
(see Study 20000)Target Affinity Spectrum Value | HUGO Gene Name |
---|---|
Dhodh | |
2 (equivalent to 100 nM ≤ Kd < 1µM) | Dhodh |
10 (confirmed non-binding) |
Batch Information for HMSL10414-101-1:
HMS LINCS Batch ID: | 10414-101-1 |
Provider: | MedChem Express |
Provider Batch ID: | 11752 |
Salt: | 101 |
Molecular Formula: | C12H9F3N2O2 |
Molecular Weight: | 270.21 |
Purity: | |
Purification Method: | |
Chemical Synthesis Reference: | |
Comments: | |
Date Publicly Available: | 2015-08-27 |
Most Recent Update: | 2016-04-04 |
HMS QC Testing Events for HMSL10414-101-1:
Date | HMS QC Outcome | Comment | Files |
---|---|---|---|
08/31/2015 | PASS | HMSL10414-101-1_LCMS.pdf |
(Kd <100 nM)